Deep Isolation’s Contrarian Take: Why Tackling the Hardest Problem First Accelerated Their GTM Success

Conventional startup wisdom says to start with the easiest problem and work your way up. But what if solving your industry’s most difficult challenge could become your fastest path to market? In a recent episode of Category Visionaries, Elizabeth Muller revealed how Deep Isolation turned nuclear waste disposal’s biggest obstacle into their competitive advantage.

The Nuclear Industry’s Impossible Challenge

The nuclear industry faced a seemingly insurmountable problem. As Elizabeth explains: “As of today, nobody in the world has ever successfully disposed of spent nuclear fuel or high level waste.” This wasn’t just a technical challenge – it was “the number one reason that people oppose nuclear power.”

Most startups would avoid such a controversial challenge. Deep Isolation made it their primary target.

Why Choose the Hardest Problem First?

Elizabeth offers a compelling rationale for tackling massive challenges: “If it’s a small problem, somebody else can do it. But if it’s a big problem and nobody else is trying to tackle it, I mean, obviously only if you have a vision for how to get it done. But if you do have a vision for getting it done and nobody else is doing it, well, that’s where you have the chance to really change the world.”

This perspective fundamentally shaped their go-to-market strategy.

Turning Industry Failure into Opportunity

The nuclear industry had a particularly notorious challenge around public demonstrations. As Elizabeth reveals: “The Department of Energy in the United States had attempted to do a demonstration of boreholes for disposal of nuclear waste… And it had failed multiple times because of public protests and people not wanting this in their backyard.”

These failures had created an industry consensus: “Word on the street was nobody could ever do a demonstration of nuclear waste disposal in the United States, certainly not with community support.”

The Power of the “First Miracle”

Instead of trying to work around this challenge, Deep Isolation tackled it head-on. Their successful 2019 demonstration became what Elizabeth calls “our first miracle” – achieving what the industry thought impossible.

This single achievement transformed their market position in ways no traditional marketing could match. “That led to partnerships with very established, significant companies,” Elizabeth explains. These partnerships completely changed how they approached government sales.

From Technical Win to Market Leadership

The success created a domino effect. As Elizabeth describes: “It wasn’t know Crazy Liz and startup company, Deep Isolation, going in to talk to the governments. It was crazy Liz and her startup team that included some very big name companies who are now going out to meet with governments around this solution that has been accepted by the industry.”

Their approach to the industry’s biggest challenge had become their strongest credential.

The Framework Behind the Strategy

Deep Isolation’s contrarian approach reveals a framework for turning industry challenges into competitive advantages:

Identify the challenge everyone else has given up on
Build a fundamentally different solution approach
Demonstrate success in a way that changes industry perception
Use that success to attract strategic partnerships
Transform partnerships into market leadership

Embracing the Messy Reality

This strategy isn’t without challenges. Elizabeth describes what she calls “the messy middle” – the complex period between initial vision and market success: “At the beginning, the early stages, it’s all excitement and energy, and everything’s just amazing. And you have this powerful vision, and then you get to the middle and it just gets complicated.”

The key is maintaining flexibility while pursuing your vision. As Elizabeth advises: “Don’t think you know where you’re going to be in twelve months time, 24 months time, 36 months time. You can always plan for it. You need to have a plan. You need to have a vision. But how you get there is going to change.”

The Competitive Advantage of Hard Problems

For founders considering their market entry strategy, Deep Isolation’s experience suggests that the conventional wisdom of starting small might actually slow you down. When you solve a problem everyone else has given up on, you create a form of competitive advantage that’s hard to replicate.

As Elizabeth puts it: “Some of us sort of laughingly say yes, maybe I should have started with something a little bit easier.” But their success in tackling nuclear waste disposal’s biggest challenge has become their strongest market differentiator.

The lesson for founders? Sometimes the fastest path to market leadership is through your industry’s hardest problem.